Analysıs of Urınary Albumın and Urınary Synaptopodın Levels in Type 2 Dıabetes Mellıtus Subjects

Hyperglycemia from diabetes mellitus affects many body organs and interferes with normal function. Kidney function decreased in approximately one-third of patients before the development albuminuria. The purpose this study was to analyze differences urine albumin synaptopodin levels type 2 (T2DM) non-DM subjects, T2DM subjects without nephropathy, correlation between cut-off analysis sensitivity specificity urinary diagnosing diabetic nephropathy. A sample 60 comprised 40 20 subjects. Urinary were examined using ELISA method, albuminuria immunoturbidimetric method. Based on statistical analysis, results showed that there (p*= < 0.001), no nephropathy 0.090), a relationship found 0.048, r= 0.314) cut off ³0.39 ng/mL, 64.7% 56.5%. We recommend further prospective studies larger sizes compare microalbuminuria (MAU) as markers for early detection DN